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Alternative methods

Alternative methods:
  • In Vitro Skin Corrosion: Transcutaneous Electrical Resistance Test based on the OECD Guideline for the Testing of Chemicals No. 430/EU Method B.40. The study is the first step leading to the determination of the acute dermal irritation/corrosion. It broadens the in vivo test described in the OECD Guideline No. 404/EU Method B.4. without causing any pain and suffering of animals. It allows the identification of corrosive properties of chemical substances and preparations without using living animals; however, it does not provide any information on skin irritation and does not make it possible to categorize chemical substances and preparations according to the Globally Harmonized System (GHS).
  • Isolated Chicken Eye Test Method for Identifying Ocular Corrosives and Severe Irritants based on the OECD Guideline for the Testing of Chemicals No. 438.
At the moment, some new alternative methods are being introduced


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Most important events

1947The Experimental-Research Station of Pesticides of the Azot Chemical Plant in Jaworzno and the Laboratory of Potato Beetle Biology and Control were founded in the place of the former School of Rural Household in Pszczyna.
1951The Experimental-Research Station of Pesticides was transferred to the Institute of Dyes and Semi-Manufactured Articles in Warsaw.
1957The Institute of Industrial Organic Chemistry in Pszczyna was founded as one of four branches of the main Institute of Industrial Organic Chemistry in Warsaw.
1960The following two research departments were founded:
  • Department of Pesticide Biological Effectiveness Evaluation
  • Department of Pesticide Side-Effects.

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